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Genetic Tools

Genetic Tools

Resources for the community.

Nature Communications 2024

Kalium Channelrhodopsins (KCR)

Comparative evaluation of light-gated potassium-conducting channelrhodopsins as neuronal inhibitors in Drosophila, C. elegans, and zebrafish. KCR1-ET matches ACR1 potency while avoiding the depolarising artefact that chloride conductance produces in high-chloride cells β€” including axons.

β†’ Nature Communications
bioRxiv 2026

LSSmScarlet3 for Two-Photon Imaging

A long-Stokes-shift mScarlet variant that can be co-imaged with GCaMP using a single 920-nm laser in Drosophila. Simplifies two-photon setups by eliminating the need for a second excitation wavelength when using a red structural marker alongside a green calcium indicator.

β†’ bioRxiv