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Sangyu Xu
徐桑榆
Computational Behaviour Scientist
Read my CV →
I’m a computational behavior scientist with 15+ years building tools that model complex, ambiguous systems. I am currently a Senior Research Fellow at the Adam Claridge-Chang Lab.
Hot Off the Press · Neuroscience · Methods
What Is a Hungry Fly?
Hunger and satiety are not single behaviors — they are coordinated internal states, expressed across many dimensions at once. On tracking thousands of Drosophila to understand how serotonin implements hunger, and what it takes to prove a neural manipulation actually changed the state rather than just one metric.
→ Read the essay bioRxiv ↗
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Getting Over ANOVA
DABEST2 — a framework that replaces p-values with bootstrap confidence intervals and effect size estimation for multiplex comparisons, following the 2,000+ citations predecessor DABEST. Binary significance testing gives you vibes. Estimation gives you evidence.
→ Read more Demo ↗
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What Is a Hungry Fly?
Tracking thousands of Drosophila across millions of frames to understand howserotonin implements hunger states. Custom hardware, computer vision, 17 behavioural metrics, high-dimensional statistics. The question: how do you know if amanipulation actually changed the state, or just one metric?
→ Read more
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Four Agents, No Ground Truth
A biologist, a bioinformatician, a reviewer, and an editor — all LLMs, arguingabout a manuscript. The easy part was building it. The hard part: how do you know it’s accurate? how much does a human have to sit on the loop?
Lanting on GitHub ↗